Synthetic accesses to biguanide compounds

Synthetic Compounds in Mandarin

This paper takes Chinese five-syllable compounds as examples to re-examine the derivation of Chinese synthetic compounds. With phonological evidences which show that Chinese synthetic compounds are left stressed, the paper proves that Chinese synthetic compounds are derived in the interface of lexicon and syntax, based on argument structures of the root verbs. The paper assumes that Chinese syn...

Synthetic Musk Compounds: Luckenbach Responds

Symptoms We read with interest the recent study titled “Neurologic Symptoms in Licensed Private Pesticide Applicators in the Agricultural Health Study” (Kamel et al. 2005). Although this was a hypothesis-generating study, the authors speculated regarding moderate exposure and associations with neurologic symptoms. Substantiation of hypotheses requires meaningful metrics of exposure and effect, ...

Biotechnology and synthetic chemistry-routes to clinically important compounds

The combination of plant cell culture methodology with synthetic chemistry affords an attractive route to the synthesis of complex natural products and related compounds of industrial importance. Plant cell cultures which often provide "unique" enzyme systems can be employed effectively as "reagents" in the biotransformation of synthetic substrates to desired end products. Such conversions are ...

Environmental and human health concerns relating to synthetic musk compounds

A study of the action of hypoglycemia-producing biguanide and sulfonylurea compounds on oxidative phosphorylation.

The mechanism of the process of oxidative phosphorylation in the respiratory chain is still quite obscure. One approach to its study has involved an investigation of inhibitors of this phenomenon (l-3). Thus, by use of various inhibitory compounds of known chemical composition some knowledge may be gleaned of the sequence of reactions comprising the over-all process, and of the nature of variou...